상세정보
등록 생체 시료를 이용한 알츠하이머 질병의 진단 방법
- 출원번호
- 13843574 (2013.03.15)
- 공개번호
- 20130337466 (2013.12.19)
- 등록번호
- 9541561 (2017.01.10)
- 출원국
- 미국
- 협약과제
- 11SF1300, 생체진단 가능 시각/미각 수용체 기반 센싱 기술 개발, 송기봉
- 초록
- Provided is a method for diagnosing Alzheimer/s disease using a decomposed biomaterial. The method includes: preparing magnetic particles on which primary capture antibodies specifically bound to beta-amyloid are adsorbed; decomposing a biomaterial including beta-amyloid; binding the beta-amyloid to the primary capture antibodies; binding secondary capture antibodies labeled with a fluorescent material to the magnetic particles bound to the beta-amyloid to form a complex; disposing the complex in a channel region of a photo field effect transistor in which a photocurrent is changed according to the amount of incident light; and measuring the photocurrent changed by light excited from the complex to quantify the concentration of the beta-amyloid existing in the biomaterial.
- KSP 제안 키워드
- Beta-amyloid, Field-effect transistors(FETs), Fluorescent material(FM), field effect, magnetic particles, s disease