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Journal Article Eco-Friendly Atom-Economical Synthesis of 2-Substituted-Benzo[d]Thiazoles and 2-Substituted-Benzo[d]Oxazoles Using 2-Acylpyridazin-3(2H)-Ones
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Authors
Gi Hyeon Sung, In-Hye Lee, Bo Ram Kim, Dong-Soo Shin, Jeum-Jong Kim, Sang-Gyeong Lee, Yong-Jin Yoon
Issue Date
2013-04
Citation
Tetrahedron, v.69, no.17, pp.3530-3535
ISSN
0040-4020
Publisher
Elsevier
Language
English
Type
Journal Article
DOI
https://dx.doi.org/10.1016/j.tet.2013.02.093
Abstract
Efficient and green syntheses of heterocycles are of great importance. In this work, we have demonstrated the synthesis of benzo[d]thiazoles and benzo[d]oxazoles using 2-acylpyridazin-3(2H)-ones as acyl transfer agents under transition-metal-free and eco-friendly conditions. It is worthy to note that the reaction is efficient, green, and economical, and will find several applications in organic synthesis, medicinal chemistry, and industrial chemistry.© 2013 Elsevier Ltd. All rights reserved.
KSP Keywords
Acyl transfer, Eco-friendly, Green syntheses, Medicinal chemistry, Transition-metal-free, industrial chemistry, organic synthesis