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Eco-Friendly Atom-Economical Synthesis of 2-Substituted-Benzo[d]Thiazoles and 2-Substituted-Benzo[d]Oxazoles Using 2-Acylpyridazin-3(2H)-Ones
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- Authors
- Gi Hyeon Sung, In-Hye Lee, Bo Ram Kim, Dong-Soo Shin, Jeum-Jong Kim, Sang-Gyeong Lee, Yong-Jin Yoon
- Issue Date
- 2013-04
- Citation
- Tetrahedron, v.69, no.17, pp.3530-3535
- ISSN
- 0040-4020
- Publisher
- Elsevier
- Language
- English
- Type
- Journal Article
- Abstract
- Efficient and green syntheses of heterocycles are of great importance. In this work, we have demonstrated the synthesis of benzo[d]thiazoles and benzo[d]oxazoles using 2-acylpyridazin-3(2H)-ones as acyl transfer agents under transition-metal-free and eco-friendly conditions. It is worthy to note that the reaction is efficient, green, and economical, and will find several applications in organic synthesis, medicinal chemistry, and industrial chemistry.© 2013 Elsevier Ltd. All rights reserved.
- KSP Keywords
- Acyl transfer, Eco-friendly, Green syntheses, Medicinal chemistry, Transition-metal-free, industrial chemistry, organic synthesis