상세정보
학술지
Synthesis of β-Ketonitriles, α,β-Alkynones and Biscabinols from Esters Using Tert-Butoxide-Assisted C(=O)-C (i.e., acyl-C) Coupling under Ambient Conditions
- 저자
- 김보람, 이형근, 강성범, 정광주, 성기현, 김점종, 이상경, 윤용진
- 발행일
- 201312
- 출처
- Tetrahedron, v.69 no.48, pp.10331-10336
- ISSN
- 0040-4020
- 출판사
- Elsevier
- 초록
- We demonstrated the synthesis of 棺-ketonitriles, 慣,棺- alkynones, and biscarbinols using tert-butoxide-assisted C(CO)-C (i.e., acyl-C) coupling of esters under ambient conditions. tert-Butoxide-assisted C(CO)-C (i.e., acyl-C) coupling of esters with cyanomethylenes and acetylenes under transition metal-free ambient conditions gives 棺-ketonitriles, 慣,棺-alkynones and/or aryl bis(phenylethynyl)carbinols in moderate-to-good yields. It is noteworthy that this is a rapid, facile, and efficient process under ambient conditions, and use of cheap and stable starting materials. © 2013 Elsevier Ltd. All rights reserved.
- KSP 제안 키워드
- Metal-free, Transition metal, ambient conditions, tert-butoxide(Niobium penta)