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Journal Article
EPITRANS: A Database that Integrates Epigenome and Transcriptome Data
- Authors
- Soo Young Cho, Jin Choul Chai, Soo Jun Park, Hyemyung Seo, Chae-Bong Sohn, Young Seek Lee
- Issue Date
- 2013-11
- Citation
- Molecules and Cells, v.36, no.5, pp.472-475
- ISSN
- 1016-8478
- Publisher
- Springer
- Language
- English
- Type
- Journal Article
- Abstract
- Epigenetic modifications affect gene expression and thereby govern a wide range of biological processes such as differentiation, development and tumorigenesis. Recent initiatives to define genome-wide DNA methylation and histone modification profiles by microarray and sequencing methods have led to the construction of databases. These databases are repositories for international epigenetic consortiums or provide mining results from PubMed, but do not integrate the epigenetic information with gene expression changes. In order to overcome this limitation, we constructed EPITRANS, a novel database that visualizes the relationships between gene expression and epigenetic modifications. EPITRANS uses combined analysis of epigenetic modification and gene expression to search for cell function-related epigenetic and transcriptomic alterations (Freely available on the web at http://epitrans.org). © The Korean Society for Molecular and Cellular Biology. All rights reserved.
- KSP Keywords
- Biological processes, Cell function, Cellular Biology, Combined analysis, DNA methylation, Epigenetic modification, Freely available, Genome-wide, Histone modification, Transcriptome data, gene expression
This work is distributed under the term of Creative Commons License (CCL)
(CC BY NC SA)
(CC BY NC SA)
