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Conference Paper
Single Cell-capturing Device in High Flow Rates with Controlled Microstructure Shapes and Their Arrangements
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- Issue Date
- 2016-10
- Citation
- International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS) 2016, pp.274-275
- Language
- English
- Type
- Conference Paper
- Abstract
- In this manuscript, design, fabrication and characterization of a simple and rapid single circulating tumor cells-capturing device with the three geometry-controlled microstructures and their gap control in form of a disposable chip have reported. We have designed a variety of microstructures for effective single cell capturing with a simulator. We have fabricated a PDMS-glass chip with the 3 kinds of designed microstructures. Finally, we have demonstrated a high capturing performance of about 70 % at a flow rate of 300 μ/min at the zigzag-arranged left-turned isosceles trapezoid.
- KSP Keywords
- Cell capturing, Circulating tumor cells(CTC), Controlled microstructure, Fabrication and characterization, Gap control, High flow rates, Single cell, glass chip, simple and rapid