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Journal Article
Electrochemical and in Vitro Neuronal Recording Characteristics of Multi-electrode Arrays Surface-modified with Electro-co-deposited Gold-platinum Nanoparticles
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- Issue Date
- 2016-02
- Citation
- Biomedical Microdevices, v.18, no.1, pp.1-7
- ISSN
- 1387-2176
- Publisher
- Springer
- Language
- English
- Type
- Journal Article
- Project Code
- 16ZH1200, Real-time bi-directional interfacing of neuron-computer and biomimetic synapse technology, Jung Sang Don
- Abstract
- In order to complement the high impedance electrical property of gold nanoparticles (Au NPs) we have performed electro-co-deposition of gold-platinum nanoparticles (Au-Pt NPs) onto the Au multi-electrode array (MEA) and modified the Au-Pt NPs surface with cell adhesive poly-D-lysine via thiol chemistry based covalent binding. The Au-Pt NPs were analyzed to have bimetallic nature not the mixture of Au NPs and Pt NPs by X-ray diffraction analysis and to have impedance value (4.0 × 104혻廓 (at 1혻kHz)) comparable to that of Pt NPs. The performance of Au-Pt NP-modified MEAs was also checked in relation to neuronal signal recording. The noise level in Au-Pt NP-modified MEAs was lower than in that of Au NP-modified MEA.
- KSP Keywords
- Au nanoparticles(Au-NPs), Electro-co-deposition, Gold-platinum nanoparticles, Multi-electrode array, Neuronal recording, Poly-d-lysine, Pt NPs, Surface-modified, Thiol chemistry, X-ray diffraction analysis, covalent binding