상세정보
학술지
Electrochemical and in Vitro Neuronal Recording Characteristics of Multi-electrode Arrays Surface-modified with Electro-co-deposited Gold-platinum Nanoparticles
- 발행일
- 201602
- 출처
- Biomedical Microdevices, v.18 no.1, pp.1-7
- ISSN
- 1387-2176
- 출판사
- Springer
- 협약과제
- 16ZH1200, 실시간 뉴런-컴퓨터 양방향 통신 및 생체모방 시냅스 기술, 정상돈
- 초록
- In order to complement the high impedance electrical property of gold nanoparticles (Au NPs) we have performed electro-co-deposition of gold-platinum nanoparticles (Au-Pt NPs) onto the Au multi-electrode array (MEA) and modified the Au-Pt NPs surface with cell adhesive poly-D-lysine via thiol chemistry based covalent binding. The Au-Pt NPs were analyzed to have bimetallic nature not the mixture of Au NPs and Pt NPs by X-ray diffraction analysis and to have impedance value (4.0 × 104혻廓 (at 1혻kHz)) comparable to that of Pt NPs. The performance of Au-Pt NP-modified MEAs was also checked in relation to neuronal signal recording. The noise level in Au-Pt NP-modified MEAs was lower than in that of Au NP-modified MEA.
- KSP 제안 키워드
- Au nanoparticles(Au-NPs), Electro-co-deposition, Gold-platinum nanoparticles, Multi-electrode array, Neuronal recording, Poly-d-lysine, Pt NPs, Surface-modified, Thiol chemistry, X-ray diffraction analysis, covalent binding