상세정보
학술지
2-Substitued-Pyridazin-3(2H)-Ones as Green Electrophilic Agents in Synthesis
- 저자
- 성기현, 김보람, 이상경, 김점종, 윤용진
- 발행일
- 201204
- 출처
- Current Organic Chemistry, v.16 no.7, pp.852-858
- ISSN
- 1385-2728
- 출판사
- Bentham Science Publishers
- 협약과제
- 12ZK1100, 그린IT 융.복합 기술개발, 이수인
- 초록
- Pyridazin-3(2H)-ones are inexpensive, stable, and easily prepared heterocycles. Since pyridazin-3(2H)-ones readily form stable anions, and can act as good leaving group. Their utility as synthetic auxiliaries was recently demonstrated by Yoon's group. 2-Substituted-pyridazin-3(2H)-ones are also useful both the electrophilic agents and equivalents for the functionalization of the electron rich compounds and active methylenes, and synthones. 2-Substituted-pyridazin-3(2H)-ones are novel green agents because that can be recovered quantitatively and recycled. In this review, the preparation and the synthetic application of 2-substituted-pyridazin-3(2H)-ones are described. © 2012 Bentham Science Publishers.
- KSP 제안 키워드
- Electron-rich, Form stable, Leaving group