BROWSE
Detail
Journal Article
2-Substituted-pyridazin-3(2H)-ones as Green Electrophilic Agents in Synthesis
Cited 12 time in 
Share 
Share
- Authors
- Gi Hyeon Sung, Bo Ram Kim, Sang-Gyeong Lee, Jeum-Jong Kim, Yong-Jin Yoon
- Issue Date
- 2012-04
- Citation
- Current Organic Chemistry, v.16, no.7, pp.852-858
- ISSN
- 1385-2728
- Publisher
- Bentham Science Publishers
- Language
- English
- Type
- Journal Article
- Abstract
- Pyridazin-3(2H)-ones are inexpensive, stable, and easily prepared heterocycles. Since pyridazin-3(2H)-ones readily form stable anions, and can act as good leaving group. Their utility as synthetic auxiliaries was recently demonstrated by Yoon's group. 2-Substituted-pyridazin-3(2H)-ones are also useful both the electrophilic agents and equivalents for the functionalization of the electron rich compounds and active methylenes, and synthones. 2-Substituted-pyridazin-3(2H)-ones are novel green agents because that can be recovered quantitatively and recycled. In this review, the preparation and the synthetic application of 2-substituted-pyridazin-3(2H)-ones are described. © 2012 Bentham Science Publishers.
- KSP Keywords
- Electron-rich, Form stable, Leaving group