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Journal Article Magnetically-actuated Blood Filter Unit Attachable to Pre-made Biochips
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Authors
Kwang Hyo Chung, Yo Han Choi, Jong-Heon Yang, Chan Woo Park, Wan-Joong Kim, Chil Seong Ah, Gun Yong Sung
Issue Date
2012-12
Citation
Lab on a Chip, v.12, no.18, pp.3272-3276
ISSN
1473-0197
Publisher
Royal Society of Chemistry (RSC)
Language
English
Type
Journal Article
DOI
https://dx.doi.org/10.1039/c2lc40529f
Abstract
We present a novel blood filter unit that is designed to separate blood plasma from whole blood by simple magnetic actuation. A non-diluted blood sample is dropped into the filter unit and magnetic attraction is applied to squeeze out only blood plasma while blood particles are filtered by membranes stacked in the filter unit. The new filter device yields good filtering performance with nearly perfect filtering efficiency (~99.999%), high plasma recovery (~30%), low blood consumption (<50 μl), and fast operation (~1 min). Because it is simple to operate and is attachable to any kind of pre-made biochip, it has commercial potential in various lab-on-a-chip applications for blood tests. © 2012 The Royal Society of Chemistry.
KSP Keywords
Blood plasma, Blood sample, Blood tests, Commercial potential, Lab on a Chip(LoC), Magnetic Actuation, Plasma recovery, Squeeze out, fast operation, magnetic attraction, whole blood