상세정보
학술지
Toxicity Bioassay in Sprague -Dawley Rats Exposed to 20 kHzTriangular Magnetic Field for 90 Days
- 저자
- 김성호, 이해윤, 최수용, 김윤명, 백정기, 최형도, 이윤실
- 발행일
- 200602
- 출처
- Bioelectromagnetics, v.27 no.2, pp.105-111
- ISSN
- 0197-8462
- 출판사
- John Wiley & Sons
- 협약과제
- 06MR2200, 전자파 영향 표준화 연구, 최형도
- 초록
- Sprague-Dawley rats (10 each of male and female per group for sham and magnetic field exposed) were exposed in a carrousel irradiator to 20 kHz intermediate frequency (IF) magnetic field at 6.25 μT rms for 8 h/day, 5 days/week for 90 days. Urine analysis (pH, serum glucose, protein, ketone bodies, RBC, WBC, bilirubin, urobilinogen, and specific gravity), blood analysis [WBC, RBC, hemoglobin, hematocrit, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), thrombocyte count, and leucocyte count], blood biochemistry (total protein, blood urea nitrogen, creatinine, glucose, total bilirubin, total cholesterol, aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, and lactate dehydrogenase), and histopathological analysis for organs such as liver, kidney, testis, ovary, spleen, brain, heart, and lung were performed on day 90. Results showed no significant differences in the above analyses between IF magnetic field exposed and sham control rats. Therefore, we conclude that there were no significant toxicities in rats exposed to 20 kHz IF triangular magnetic field-exposure for 90 days. © 2005 Wiley-Liss, Inc.
- KSP 제안 키워드
- Alanine aminotransferase, Alkaline phosphatase(ALP), Aspartate aminotransferase, Blood analysis, Blood biochemistry, Intermediate frequency, Lactate dehydrogenase(LDH), Magnetic field(MF), Mean corpuscular hemoglobin concentration, Serum glucose, Specific gravity