상세정보
학술대회
Plastic-Silicon PCR Amplification System Made Using Microfabrication Technologies
- 발행일
- 200610
- 출처
- IEEE Sensors 2006, pp.592-595
- 협약과제
- 05MB3500, e-Health 구현을 위한 바이오 센서 기술 개발, 최창억
- 초록
- We present a novel polyimide micro-heat control system, embedding with a micro heater and a temperature sensor, and silicon reaction chamber for polymerase chain reaction (PCR). We have demonstrated a precise heat control, and rapid thermal response in the chip, and the chip successfully amplified PCR of a genomic DNA template (breast cancer suppressor gene, BRCA 1 127 base pairs) in a 3 μI-volume chamber within 18 min, extracted from the human whole blood, and it is applicable a lab-on-a-chip for precise, fast, efficient and cost-effective DNA analysis, including biomedical applications and disease diagnostics. © 2006 IEEE.
- KSP 제안 키워드
- Base pairs, Biomedical applications, Breast Cancer(BC), DNA Analysis, DNA template, Genomic DNA, Heat control system, Human whole blood, Lab on a Chip(LoC), Micro-heater, Microfabrication technologies