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학술지 Sensitivity Response to Coating Material Thickness for an Optical Resonant Reflective Biosensor Based on a Guided Mode Resonance Filter
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저자
김봉규, 김경현, 홍종철, 김완중, 고현성, 허철, 성건용, 장원익, 박선희, 박수준
발행일
201403
출처
BioChip Journal, v.8 no.1, pp.35-41
ISSN
1976-0280
출판사
한국바이오칩학회
DOI
https://dx.doi.org/10.1007/s13206-014-8106-2
협약과제
14PC2600, 유방암수술시 전이부위 실시간 판독이 가능한 형광(심도>10mm)및 광음향(분해능<60um@30Mhz,심도>60mm@10MHz)융합 프로브 기술 개발, 김봉규
초록
Sensitivity is a very important parameter for biosensor applications. We have numerically and experimentally studied the sensitivity and linewidth responses of optical resonant reflective biosensors to the thickness of high refractive index materials coating the grating layer used to create a guided mode. Zero sensitivity, which may create serious problems in biosensors, is obtained when the coating material has a relatively low refractive index and a thin coating thickness (near the cutoff condition in which a high index layer is no longer capable of acting as a waveguide). The sensitivity and linewidth are greatly influenced by the thickness of the coating material. The thickness also has an optimal state, which is a very important factor for designing highly sensitive optical resonant reflective biosensors using a guided mode resonance filter. © 2014 The Korean BioChip Society and Springer-Verlag Berlin Heidelberg.
KSP 제안 키워드
Coating Thickness, Guided mode resonance filter(GMRF), Guided-mode resonance(GMR), High index, Highly sensitive, Low refractive index, Optimal state, coating materials, high refractive index materials, material thickness, thin coating