상세정보
학술지
A New Strategy for Chemoselective O-acylation of β-mercapto Alcohols via Alkylsilyl and Stannyl Protection
- 저자
- Muchchintala Maheswara, 김미래, 윤선주, 주정진, 도정윤
- 발행일
- 200901
- 출처
- Tetrahedron Letters, v.50 no.4, pp.480-483
- ISSN
- 0040-4039
- 출판사
- Elsevier
- 협약과제
- 08MB2200, 휴대 단말기용 나노 플렉시블 광전배선 모듈, 주정진
- 초록
- Chemoselective preparation of O-acylated derivatives from bis-protected mercapto alcohols was described. Trialkylsilyl and trialkylstannyl chloride are used to generate an intermediate with O- and S-protection. The intermediates from 棺-mercapto alcohols are reactive toward acylating agents and selective to provide O-acylated derivatives. The present preparation involves the direct conversion of alcohol to the corresponding O-acylated compounds without deprotection. © 2008 Elsevier Ltd. All rights reserved.
- KSP 제안 키워드
- Direct Conversion, New strategy, O-acylation