ETRI-Knowledge Sharing Plaform

KOREAN
논문 검색
Type SCI
Year ~ Keyword

Detail

Journal Article Enhancement of Neuronal Cell Adhesion by Covalent Binding of Poly-D-Lysine
Cited 72 time in scopus Share share facebook twitter linkedin kakaostory
Authors
Yong Hee Kim, Nam Seob Baek, Young Hwan Han, Myung-Ae Chung, Sang-Don Jung
Issue Date
2011-10
Citation
Journal of Neuroscience Methods, v.202, no.1, pp.38-44
ISSN
0165-0270
Publisher
Elsevier
Language
English
Type
Journal Article
DOI
https://dx.doi.org/10.1016/j.jneumeth.2011.08.036
Abstract
We have prepared the poly-d-lysine (PDL) bound surfaces for neuron cell culture by covalent binding between the poly-d-Lysine and substrates and investigated neuronal cell adhesion properties and cell growth morphology. The number of neuronal cell and the number of neurite per neuronal cell on PDL bound surfaces was much more than those on PDL coated surfaces and also the neuronal cells on PDL bounded surfaces survived a longer time. On the pattern of covalently bound PDL, neuronal cells and their neurites are confined within the grid line leading to patterned neuronal networks with the long-term survival. © 2011 Elsevier B.V.
KSP Keywords
Cell Adhesion, Cell Culture, Cell growth, Growth morphology, Neuronal networks, Poly-d-lysine, adhesion properties, coated surfaces, covalent binding, neuronal cells