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학술지 Use of Gas-Sensor Array Technology in Lung Cancer Diagnosis
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저자
김용준, 유한영, 백인복, 안창근, 이봉국, 김약연, 윤용선, Ji Eun Lim, 이병준, 장원익, Jeong Ho Park, Chang-Auck Choi
발행일
201307
출처
센서학회지, v.22 no.4, pp.249-255
ISSN
1225-5475
출판사
한국센서학회
DOI
https://dx.doi.org/10.5369/JSST.2013.22.4.249
초록
Gas-sensor array technology, which has been much utilized in the field of food technology by the name of 'Æelectronic nose', is drawing attention in diagnosing lung cancer based on the analysis of the exhaled human breath. Much understanding has been accomplished about the composition of the volatile organic compounds (VOCs) of the human exhaled breath, in spite of some variations depending on research groups due mainly to lack of the standardization of the sensing procedures. Since VOCs may be produced during the process of cellular metabolism, difference in the cellular metabolism between healthy cells and lung cancer cells are expected to be reflected on the composition variation of the exhaled VOCs. Several studies have attempted to apply the gas-sensor array technology to lung cancer analysis using many different types of sensors including metal oxide, carbon black-polymer composite, surface acoustic wave, and gold nanoparticles. In this mini-review VOC as biomarkers, sensor array technology and application of the array technology for the diagnosis of cancer disease have been described.
KSP 제안 키워드
Array technology, Carbon black-polymer composite, Cellular metabolism, Food technology, Human exhaled breath, Lung cancer diagnosis, Metal-oxide(MOX), Mini-review, Surface acoustic wave(SAW), gas sensor array, gold nanoparticles(NPs)