상세정보
학술지
Enhanced Protein Immobilization Efficiency on a TiO2 Surface Modified with a Hydroxyl Functional Group
- 발행일
- 200910
- 출처
- Langmuir, v.25 no.19, pp.11692-11697
- ISSN
- 0743-7463
- 출판사
- American Chemical Society(ACS)
- 초록
- An antibody immobilization was investigated using a self-assembled monolayer (SAM) over the highly refractive coatings with a SiO2, TiO2, or Si3N4 substrate. The immobilization was characterized by analyzing the hydrophilic properties of hydroxyl (OH) groups on surface coatings with contact angle (CA) measurements to enhance protein immobilization. The hydroxyl (OH) group was formed in greater amounts as the oxygen plasma exposure time was increased, which resulted in a large enhancement in antibody immobilization. It indicated that hydroxyl (OH) group formation is critical for developing a label-free optical transducer with a high sensitivity. © 2009 American Chemical Society.
- KSP 제안 키워드
- Contact angle(CA), Exposure time, Group Formation, High Sensitivity, Hydrophilic properties, Hydroxyl functional group, Label-Free, Optical transducer, Refractive coatings, Surface-modified, antibody immobilization