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Conference Paper Micro Membrane Filters for Passive Plasma Extraction From Whole Human Blood Using Silicon Nitride-based Microfilters and Plama Collection Using Agarose Gels
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Authors
D.S. Lee, Y.H. Choi, K.H. Chung, S. Shoji, M.Y. Jung
Issue Date
2009-09
Citation
EuroSensors 2009, pp.1511-1514
Language
English
Type
Conference Paper
DOI
https://dx.doi.org/10.1016/j.proche.2009.07.377
Abstract
The novelty of this study resides in the fabrication of a passive, operating on capillary force, penetration-flow microfluidic device for plasma separation, based on both silicon nitride combination (SiN-SiO-SiN)-based microfilters and agarose gels, and its characterization for plasma separation from whole human blood. The fabrication processes are compatible with IC process protocols, with merits of mass productions and precise size control. The fabrication process for silicon nitride membrane was reported at Lab Chip [1], and quantification its applications to affinity-based protein separation on the silicon nitride was reported at MicroTAS'07 [2]. Our method differs from that of group Yobas [3] in the specific separation method and materials, and of group Pizziconi [4] in the geometry of the filter, and fluidic components with the structure. © 2009.
KSP Keywords
Affinity-based, Agarose gel, Fabrication process, Human blood, Micro membrane, Microfluidic device, Plasma extraction, Plasma separation, Protein separation, Separation method, capillary force
This work is distributed under the term of Creative Commons License (CCL)
(CC BY NC ND)
CC BY NC ND