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학술지 A Surface Acoustic Wave-Based Immunosensing Device Using a Nanocrystalline ZnO Film on Si
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저자
이대식, 이준황, Jikui Luo, Yongqing Fu, William I Milne, 맹성렬, 정문연, 박선희, 윤현철
발행일
200910
출처
Journal of Nanoscience and Nanotechnology, v.9 no.12, pp.7181-7185
ISSN
1533-4880
출판사
American Scientific Publishers (ASP)
DOI
https://dx.doi.org/10.1166/jnn.2009.1662
협약과제
06MB4700, 차세대 고성능 광전자소자 및 스마트 생화학 센서 구현을 위한 IT-BT-NT 융합 핵심기술 개발, 맹성렬
초록
The novelty of this study resides in the fabrication of a bio-sensing device, based on the surface acoustic wave (SAW) on a nanocrystalline ZnO film. The ZnO film was deposited using an rf magnetron sputtering at room temperature on silicon. The deposited films showed the c-axisoriented crystallite with grain size of ~40 nm. The immunosensing device was fabricated using photolithographic protocols on the film. As a model biomolecular recognition and immunosensing, biospecific interaction between a 6-(2,4-dinitrophenyl) aminohexanoic acid (DNP) antigen and its antibody was employed, demonstrating the shifts of resonant frequencies on SAW immunosensing device. The device exhibited a linearity as a function of the antibody concentration in the range of 20~20,000 ng/ml. © 2009 American Scientific Publishers. All rights reserved.
KSP 제안 키워드
40 nm, Bio-Sensing, Biomolecular recognition, Biospecific interaction, Grain size, Nanocrystalline ZnO, Resonant frequency(Fr), Room-temperature, Sensing device, Surface acoustic wave(SAW), ZnO films