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Journal Article Effects of pH and Ion Concentration in Phosphate Buffer Solution on the Sensitivity of the Silicon Nanowire BioFETs
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Authors
Jae Hyun Lee, Min Cheol Shin, Chang Guen Ahn, Chil Seong Ah, Chan Woo Park, Gun Yong Sung
Issue Date
2009-10
Citation
Journal of the Korean Physical Society, v.55, no.4, pp.1621-1625
ISSN
0374-4884
Publisher
한국물리학회 (KPS)
Language
English
Type
Journal Article
DOI
https://dx.doi.org/10.3938/jkps.55.1621
Abstract
We have developed an in-house simulator based on the self-consistent solution of the threedimensional (3D) Poisson-Boltzmann and 3D drift-diffusion equations to examine the effects of pH and ion concentration in a phosphate buffer solution on the sensitivity of a biologically-sensitive silicon nanowire field-effect transistors (BioFETs). We have analyzed the simulation results for the pH and the ion concentration in the phosphate buffer solution by using the concept of the Debye length. We have found that the Debye length is decreased by increasing the ion concentration and decreasing the pH in the phosphate buffer solution. A short Debye length and large probe molecule charges are found to affect the sensitivity of the BioFETs.
KSP Keywords
Debye length, Field-effect transistors(FETs), Phosphate buffer solution, Poisson-Boltzmann, Self-consistent solution, Silicon nanowires(SiNWs), drift-diffusion equations, ion concentration, nanowire field-effect transistors, probe molecules, simulation results