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Journal Article
Photopatterning of Cell-Adhesive-Modified Poly(ethyleneimine) for Guided Neuronal Growth
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- Authors
- Nam Seob Baek, Ji-Hyun Lee, Yong Hee Kim, Bong Joon Lee, Gook Hwa Kim, Ik-Hyun Kim, Myung-Ae Chung, Sang-Don Jung
- Issue Date
- 2011-03
- Citation
- Langmuir, v.27, no.6, pp.2717-2722
- ISSN
- 0743-7463
- Publisher
- American Chemical Society(ACS)
- Language
- English
- Type
- Journal Article
- Abstract
- We describe photopatterning technique that employs the photodegradation of cell-adhesive-modified poly(ethyleneimine) (m-PEI) to fabricate precise micropatterns on the indium tin oxide (ITO) substrate for guided neuronal growth. The photodegradation of m-PEI coated on hydroxyl group-terminated ITO substrate created micropatterns over a large area through deep UV irradiation. The photopatterned m-PEI layer can effectively guide neurite outgrowth and control neurite extensions from individual neurons. © 2011 American Chemical Society.
- KSP Keywords
- Indium Tin Oxide(ITO), Neuronal growth, deep UV irradiation, hydroxyl group, large area, neurite outgrowth