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학술지 Photopatterning of Cell-adhesive Modified Poly(ethyleneimine) for Guided Neuronal Growth
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저자
백남섭, 이지현, 김용희, Bong Joon Lee, Gook Hwa Kim, Ik-Hyun Kim, 정명애, 정상돈
발행일
201103
출처
Langmuir, v.27 no.6, pp.2717-2722
ISSN
0743-7463
출판사
American Chemical Society(ACS)
DOI
https://dx.doi.org/10.1021/la103372v
협약과제
09SC1500, 뉴런 및 수용체와 반도체 소자의 하이브리드 네트워크, 정명애
초록
We describe photopatterning technique that employs the photodegradation of cell-adhesive-modified poly(ethyleneimine) (m-PEI) to fabricate precise micropatterns on the indium tin oxide (ITO) substrate for guided neuronal growth. The photodegradation of m-PEI coated on hydroxyl group-terminated ITO substrate created micropatterns over a large area through deep UV irradiation. The photopatterned m-PEI layer can effectively guide neurite outgrowth and control neurite extensions from individual neurons. © 2011 American Chemical Society.
KSP 제안 키워드
Neuronal growth, deep UV irradiation, hydroxyl group, indium tin oxide(ITO), large area, neurite outgrowth