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Journal Article
Biotin-Functionalized Semiconducting Polymer in an Organic Field Effect Transistor and Application as a Biosensor
- Authors
- Zin-Sig Kim, Sang Chul Lim, Seong Hyun Kim, Yong Suk Yang, Do-Hoon Hwang
- Issue Date
- 2012-08
- Citation
- Sensors, v.12, no.8, pp.11238-11248
- ISSN
- 1424-8220
- Publisher
- MDPI AG
- Language
- English
- Type
- Journal Article
- Abstract
- This report presents biotin-functionalized semiconducting polymers that are based on fluorene and bithiophene co-polymers (F8T2). Also presented is the application of these polymers to an organic thin film transistor used as a biosensor. The side chains of fluorene were partially biotinylated after the esterification of the biotin with corresponding alcohol-groups at the side chain in F8T2. Their properties as an organic semiconductor were tested using an organic thin film transistor (OTFT) and were found to show typical p-type semiconductor curves. The functionality of this biosensor in the sensing of biologically active molecules such as avidin in comparison with bovine serum albumin (BSA) was established through a selective decrease in the conductivity of the transistor, as measured with a device that was developed by the authors. Changes to the optical properties of this polymer were also measured through the change in the color of the UV-fluorescence before and after a reaction with avidin or BSA. © 2012 by the authors; licensee MDPI, Basel, Switzerland.
- KSP Keywords
- Biologically active molecules, Co-polymers, Field Effect Transistor(FET), Organic Semiconductor Material(OSC), Organic field-effect transistor(OFET), Side-chain, Thin-Film Transistor(TFT), bovine serum albumin, optical properties, organic thin film transistor(OTFT), p-Type semiconductor
This work is distributed under the term of Creative Commons License (CCL)
(CC BY)
(CC BY)
