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Journal Article Near-Field Detection of Aβ Proteins Using Micro Beads
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Authors
Seung-Jun Lee, Hee-Kyung Sung, Yo-Han Choi
Issue Date
2012-10
Citation
센서학회지, v.21, no.5, pp.319-323
ISSN
1225-5475
Publisher
한국센서학회
Language
English
Type
Journal Article
DOI
https://dx.doi.org/10.5369/JSST.2012.21.5.319
Abstract
In this paper, we present the possibility of quantification analysis for $A{\beta}$ captured by micro beads using Near-filed detection. In order to evaluate detection efficiency, detected signals were compared with different sizes of micro beads and a varied number of micro beads. Also, $A{\beta}$ deposits and $A{\beta}$ binding to micro beads were measured, therefore, we observed the $A{\beta}$ deposit and light scattering around the surface of micro beads induced by attached $A{\beta}$. This method can be used for quantitative analysis for not only the number of $A{\beta}$, but also the binding ratio of $A{\beta}$ to micro beads.
KSP Keywords
Binding ratio, Detection efficiency, Different sizes, Near-field detection, Quantification analysis, light scattering, quantitative analysis