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학술지 Compressive Strength and Biomineralisation Improvement by Water Glass Coating on Porous Calcium Phosphate Scaffolds
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저자
Indu Bajpai, 양소영, 이수정, 강인규, 이준희, 김석영
발행일
201602
출처
Advances in Applied Ceramics, v.115 no.4, pp.243-248
ISSN
1743-6753
출판사
Maney Publishing
DOI
https://dx.doi.org/10.1179/1743676115Y.0000000028
협약과제
16ZC3100, 지역기반 의료기기.의료로봇 기술개발 및 의료IT 융합 중소기업 활성화 사업, 최은창
초록
Calcium phosphate (Ca-P) based scaffolds were found to be a favourable alternative for orthopaedic applications because of their similar chemical composition to natural bone. In this study, porous triphasic Ca-P scaffolds containing macropores (&200 mm) interconnected with micropores (&20 mm) were fabricated using an extrusion method. The hydroxyapatite/tricalcium phosphate ratio of the porous scaffolds was varied using different ratios of starting materials while keeping the Ca/P ratio fixed (1.5). A water glass coating on the porous Ca-P scaffolds increased the compressive strength by 45% without significantly decreasing the porosity of the H100D50 scaffold. The maximum compressive strength, ,15 MPa, was achieved on the H100D50 scaffold. The ability for apatite formation in simulated body fluid was amplified by the water glass coating on the sintered Ca-P scaffolds. Therefore, a water glass coating can be used to enhance the mechanical properties as well as the biomineralisation of the porous ceramic scaffolds.
KSP 제안 키워드
200 mm, Apatite formation, Ca/P ratio, Compressive Strength, Extrusion method, Glass coating, Mechanical properties(PMCs), Porous ceramic, Porous scaffolds, Water glass, calcium phosphate(CaP)