상세정보
학술지
A Three-Dimensional and Bevel-Angled Ultrahigh Aspect Ratio Microneedle for Minimally Invasive and Painless Blood Sampling
- 저자
- 이대식, Cheng Guo Li, 임춘화, 정형일
- 발행일
- 201802
- 출처
- Sensors and Actuators B : Chemical, v.255, pp.384-390
- ISSN
- 0925-4005
- 출판사
- Elsevier
- 협약과제
- 17JS1300, 다중 바이오마커 기반 모바일 다이어트 모니터링 기술 개발, 이대식
- 초록
- In spite of the invasiveness and pain related with it, blood sampling is necessary in point-of-care systems to obtain biochemical information. In this context, a substitute micro-scale needle for minimally invasive and painless blood sampling has been developed. In conventional microneedle fabrication methods, it is difficult to combine the features of a sharp tip shape, appropriate length, and a hollow structure simultaneously. Thus, here we report a sharp, hollow, and ultrahigh aspect ratio microneedle long enough to get to the blood vessels which is capable of minimizing the pain caused by nerve pricking. It is equipped with a fluidic system to handle blood. The structure of the microneedle was precisely formed using a drawing lithography method and a sharp angle tip was formed using a laser-cutting method.
- KSP 제안 키워드
- Blood Vessels, Blood sampling, Cutting method, Fabrication method, Fluidic system, Hollow structure, Laser-cutting, Micro-scale, Minimally invasive, Point-of-care, Sharp angle