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학술지 A High-performance Transparent Graphene/Vertically Aligned Carbon Nanotube (VACNT) Hybrid Electrode for Neural Interfacing
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저자
정두원, 김국화, 김나연, 이종훈, 정상돈, 이정오
발행일
201701
출처
RSC Advances, v.7 no.6, pp.3273-3281
ISSN
2046-2069
출판사
Royal Society of Chemistry (RSC)
DOI
https://dx.doi.org/10.1039/c6ra26836f
협약과제
16ZH1200, 실시간 뉴런-컴퓨터 양방향 통신 및 생체모방 시냅스 기술, 정상돈
초록
Neural interfaces that do not damage cells or tissues are key to connecting brain functions to neural prosthetics. Here, we designed a transparent graphene/vertically aligned carbon nanotube (VACNT) electrode capable of extracellularly recording spontaneous action potentials in Sprague-Dawley rat primary cortex neurons. Graphene provided the dual function of contacting the VACNTs and visually monitoring the cell viability. The hybrid electrodes exhibited remarkably high peak-to-peak signal amplitudes (1600 μV) and low noise levels, presumably due to tight junction formation between the cells and the deformed CNTs. Spike simulation and high-resolution transmission electron microscopy (HRTEM) imaging confirmed the excellent interfacial characteristics of the cells and the transparent hybrid electrodes.
KSP 제안 키워드
Carbon nano-tube(CNT), Cell viability, Dual function, High performance, Hybrid electrode, Interfacial characteristics, Low noise, Neural interface, Tight junction, Transmission Electron Microscopy(TEM), Vertically aligned carbon nanotube