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Conference Paper Interferometric Detection of Prostate Specific Antigen based on Enzyme Immunoassay
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Authors
Hyun-Woo Song, Yo Han Choi, Hyeon-Bong Pyo, Kwang-Hyo Chung, Dae-Sik Lee, Moon-Youn Jung, Seon Hee Park
Issue Date
2010-09
Citation
Eurosensors 2010, pp.800-803
Language
English
Type
Conference Paper
DOI
https://dx.doi.org/10.1016/j.proeng.2010.09.229
Abstract
Interferometric detection of Prostate-specific antigen (PSA) based on enzyme immunoassay are investigated. Refractive index changes of substrate are measured for PSA detection. Michelson scheme of optical interferometer was used so as to be applicable to a disposable fluidic chip. When interferometer is used for the measurements of refractive index changes, the detection is over 8 times more sensitive than that of absorbance changes for the same amount of target protein.
KSP Keywords
Enzyme immunoassay, Interferometric detection, Optical interferometer, PSA detection, Refractive index change, Target protein, prostate-specific antigen(PSA)
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(CC BY NC ND)
CC BY NC ND