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Conference Paper Optogenetic Manipulation of Neurons Using Organic Light-Emitting Diodes
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Authors
Kukjoo Kim, Congqi Yang, Yong Hee Kim, Dae Hyun Ahn, Sukyung Choi, Jin-Wook Shin, Jong-Heon Yang, Chun-Won Byun, Sang-Don Jung, Seongjun Park
Issue Date
2025-05
Citation
Society for Information Display (SID) International Symposium 2025, pp.580-582
Language
English
Type
Conference Paper
DOI
https://dx.doi.org/10.1002/sdtp.18227
Abstract
We developed tandem-structured blue and yellow OLEDs optimized for optogenetics, achieving peak optical power densities of ~3.1 mW/mm² and ~3.8 mW/mm², respectively. The emission spectra were matched to the activation spectra of opsins like ChR2 and Arch, enabling effective neuronal activation and inhibition. With a custom-made 64-channel MEA, we demonstrated precise temporal correlations between OLED stimulation and neuronal responses. These results establish OLEDs as promising light sources for optogenetic applications.
KSP Keywords
Custom-made, Emission spectra, Light source, Power Density, Temporal Correlation, light emitting diodes(LED), neuronal activation, optical power, organic light emitting diode(OLED)