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Registered APPARATUS AND METHOD FOR DETECTING

생분자 검출 장치 및 검출 방법
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Inventors
Chil Seong Ah, Kim Ansoon, Baek In Bok, Gun Yong Sung, Yang Jong-Heon, Park Seon Hee, Park Chan Woo, Chang-Geun Ahn, Tae-Youb Kim, Yu Han Young, Yang Hyekyoung, Jang Moon Gyu
Application No.
13062146 (2008.11.20)
Publication No.
20110165557 (2011.07.07)
Registration No.
8529750 (2013.09.10)
Country
UNITED STATES
Project Code
08MC2500, Ubiquitous Health Monitoring Module and System Development, Park Seon Hee
Abstract
Provided are an apparatus and method for detecting biomolecules. The apparatus includes a FET having a substrate, a source electrode, a drain electrode, a channel region between the source and drain electrodes, and probe molecules fixed to the channel region, wherein the source and drain electrodes are separated on the substrate, a microfluid supplier selectively supplying one of a reference buffer solution of low ionic concentration and a reaction solution of high ionic concentration containing target molecules, to the channel region of the FET to which the probe molecules are fixed, and a biomolecule detector detecting the target molecules by measuring a first current value of the channel region of the FET, and a second current value of the channel region of the FET to which the target molecules and the probe molecules that bind to each other in the reaction solution of high ionic concentration are fixed.
KSP Keywords
Buffer solution, Drain electrode, Source and drain, ionic concentration, probe molecules, reference buffer