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Registered BIOCHIP AND APPARATUS FOR DETECTING BIOMATERIAL USING BIOCHIP
- Inventors
- Song Hyun Woo, Yo Han Choi, Pyo Hyeonbong
- Application No.
- 12484806 (2009.06.15)
- Publication No.
- 20100159614 (2010.06.24)
- Registration No.
- 8288171 (2012.10.16)
- Country
- UNITED STATES
- Project Code
- 08MC2500, Ubiquitous Health Monitoring Module and System Development, Park Seon Hee
- Abstract
- Provided is a biochip and an apparatus for detecting a biomaterial. The biochip includes a metal thin film on the surface of a substrate, restraining autofluorescence of the substrate, and a spacer on the metal thin film, having capture molecules immobilized on the surface of the spacer and specifically bound to target molecules. The spacer has a thickness controlled to enhance the strength of a fluorescence signal emitted from a fluorophore labeled with the target molecules and immobilized on the spacer by the specific binding between the capture molecule and the target molecule.
- KSP Keywords
- Fluorescence signal, Metal thin film, specific binding, target molecule, thin film(TF)